RANKL anticorps (AA 10-90)

N° du produit ABIN7210648

Détail du produit anti-RANKL anticorps

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Épitope: AA 10-90

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANKL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Fonction: OPG Polyclonal Antibody

Specificité: OPG Polyclonal Antibody detects endogenous levels of OPG protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human OPG at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur RANKL

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Autre désignation: OPG (TNFSF11 Produits)

Synonymes: anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps TNFSF11, anticorps Ly109l, anticorps OPG, anticorps Trance, anticorps cd254, anticorps odf, anticorps opgl, anticorps optb2, anticorps rankl, anticorps sodf, anticorps tnfsf11, anticorps trance, anticorps TNF superfamily member 11, anticorps tumor necrosis factor (ligand) superfamily, member 11, anticorps TNF receptor superfamily member 11b, anticorps TNF superfamily member 11 L homeolog, anticorps TNFSF11, anticorps Tnfsf11, anticorps TNFRSF11B, anticorps tnfsf11.L

Sujet: Rabbit Anti-OPG Polyclonal Antibody,TNFRSF11B, OCIF, OPG, Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin,TNF receptor superfamily member 11b encoded by TNFRSF11B is a member of the TNF-receptor superfamily. TNF receptor superfamily member 11b is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. TNF receptor superfamily member 11b specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that TNF receptor superfamily member 11b and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of TNFRSF11B have been reported, but their full length nature has not been determined.,Tumor necrosis factor receptor superfamily member 11B

ID gène: 4982

UniProt: O00300

Pathways: Signalisation NF-kappaB