ITGB1 anticorps
-
- Antigène Voir toutes ITGB1 Anticorps
- ITGB1 (Integrin beta 1 (ITGB1))
-
Reactivité
- Souris
-
Hôte
-
Hamster arménien
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp ITGB1 est non-conjugé
-
Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
- Marque
- BD Pharmingen™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Immunogène
- Purified mouse VLA-4
- Clone
- HM BETA 1-1
- Isotype
- IgG2 lambda
- Top Product
- Discover our top product ITGB1 Anticorps primaire
-
-
- Indications d'application
- Reported applications include immunoprecipitation and in vitro inhibition (in combination with a mAb to mouse CD11a) of T-cell proliferative responses to anti-CD3e mAb 145-2C11 (Cat. no. 553057) and allogeneic cells. We recommend our immunohistochemistry formulation of purified HM beta1-1 mAb (Cat. No. 550530) for immunohistochemical staining (IHC) of rat tissues. For IHC of mouse tissues, we recommend the use of Purified Rat anti-Mouse CD29 mAb 9EG7 formulated for immunohistochemistry application (Cat. No. 550531).
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Agent conservateur
- Azide free
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
-
Identification and functional characterization of mouse CD29 with a mAb." dans: International immunology, Vol. 7, Issue 5, pp. 835-42, (1995) (PubMed).
: "Expression of a novel integrin beta 1 chain epitope and anti-beta 1 antibody-mediated enhancement of fibronectin binding are dependent on the stage of T cell differentiation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 5, pp. 2125-33, (1995) (PubMed).
: "Recognition of murine integrin beta 1 by a rat anti-stromal cell monoclonal antibody." dans: Hybridoma, Vol. 13, Issue 5, pp. 409-16, (1995) (PubMed).
: "Temporal expression of VLA-2 and modulation of its ligand specificity by rat glomerular epithelial cells in vitro." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 69, Issue 6, pp. 690-702, (1994) (PubMed).
: "Highly restricted expression of a stromal cell determinant in mouse bone marrow in vivo." dans: The Journal of experimental medicine, Vol. 176, Issue 4, pp. 927-35, (1992) (PubMed).
: "Adhesion receptors of the immune system." dans: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).
: "
-
Identification and functional characterization of mouse CD29 with a mAb." dans: International immunology, Vol. 7, Issue 5, pp. 835-42, (1995) (PubMed).
-
- Antigène
- ITGB1 (Integrin beta 1 (ITGB1))
- Autre désignation
- CD29 (ITGB1 Produits)
- Synonymes
- anticorps CD29, anticorps FNRB, anticorps GPIIA, anticorps MDF2, anticorps MSK12, anticorps VLA-BETA, anticorps VLAB, anticorps 4633401G24Rik, anticorps AA409975, anticorps AA960159, anticorps ENSMUSG00000051907, anticorps Fnrb, anticorps Gm9863, anticorps gpIIa, anticorps cd29, anticorps fnrb, anticorps gpiia, anticorps itgb1, anticorps mdf2, anticorps msk12, anticorps vla-beta, anticorps vlab, anticorps itgb1-a, anticorps itgb1-b, anticorps integrin subunit beta 1, anticorps integrin beta 1 (fibronectin receptor beta), anticorps integrin subunit beta 1 S homeolog, anticorps integrin beta 1, anticorps integrin subunit beta 1 L homeolog, anticorps ITGB1, anticorps Itgb1, anticorps itgb1.S, anticorps LOC100009173, anticorps itgb1.L
- Sujet
-
The HMbeta1-1 antibody reacts with the 130-kDa integrin beta1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin-alpha chains. With alpha1 through alpha6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with alphav (CD51), it forms alphavbeta1 integrin. It also associates with the integrin alpha7 alpha8, and alpha9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, epithelia, and oocytes. This hamster mAb to a mouse leukocyte antigen has been observed to crossreact with similar populations of rat leukocytes. Source of the immunogen was purified mouse VLA-4 (alpha4beta1, CD49d/CD29).
Synonyms: Itgb1, Integrin beta-1, Fnrb, gpIIa, VLA-4 subunit beta - Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
-