GZMB anticorps (Biotin)

N° du produit ABIN119564

L’anticorps Souris Monoclonal anti-GZMB a été validé pour EIA. Il convient pour détecter GZMB dans des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (Biotin) (ABIN119564)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est conjugé à/à la Biotin

Application: Enzyme Immunoassay (EIA)

Clone: GB10

Détail du produit anti-GZMB anticorps (Biotin)

Specificité: This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (SM1806P) as capture reagent.

Purification: Affinity chromatography on Protein A

Immunogène: Purified human Granzyme B. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.001 % Thiomersal

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Sujet: Ganzyme B which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

ID gène: 3002

NCBI Accession: NP_004122

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis