GZMB anticorps (AA 21-247)

N° du produit ABIN7193680

Détail du produit anti-GZMB anticorps

Antigène: GZMB (Granzyme B (GZMB))

Épitope: AA 21-247

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. coli.

Clone: 2G12G7

Isotype: IgG2a

Information d'application

Indications d'application: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: GZMB (GZMB Produits)

Synonymes: anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB

Sujet:

Description: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Aliases: C11, HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1

Poids moléculaire: 28 kDa

ID gène: 3002

Pathways: Apoptose, Caspase Cascade in Apoptosis