IFNA anticorps
Aperçu rapide pour IFNA anticorps (ABIN120183)
Antigène
Voir toutes IFNA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Affinity chromatography on Protein G
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Immunogène
- Recombinant chicken Interferon alpha.
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Isotype
- IgG1
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Indications d'application
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ELISA. Western Blot: this antibody detects a band of approximately 19 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IFNA (Interferon alpha (IFNA))
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Autre désignation
- Interferon alpha (IFN Alpha)
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Sujet
- The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon
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Pathways
- Signalistation JAK/STAT, Signalisation TLR, Hepatitis C, Inflammasome
Antigène
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