TNFSF18 anticorps

N° du produit ABIN120289

Détail du produit anti-TNFSF18 anticorps

Antigène: TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFSF18 est non-conjugé

Application: Flow Cytometry (FACS)

Purification: Affinity chromatography on Protein G

Immunogène: Recombinant mouse GITRL. Spleen cells from immunised DA rats were fused with cells of the Y3/Ag1.2.3 myeloma cell line.

Clone: YGL386

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1/25 - 1/50, use 10 μL of the suggested working dilution to label 106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TNFSF18

Antigène: TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

Autre désignation: TNFSF18 / AITRL (TNFSF18 Produits)

Synonymes: anticorps Gitrl, anticorps AITRL, anticorps GITRL, anticorps TL6, anticorps hGITRL, anticorps TNLG2A, anticorps tumor necrosis factor (ligand) superfamily, member 18, anticorps TNF superfamily member 18, anticorps Tnfsf18, anticorps TNFSF18

Sujet: GITRL is a 20 kD member of the tumour necrosis factor ligand superfamily, otherwise known as TNSF18. Mouse GITRL is predominantly expressed on immature and mature dendritic cells, macrophages and B cells. Expression of mouse GITRL can be transiently up regulated on these cells, following lipolysaccharide (LPS) stimulation, but protein expression is rapidly down modulated shortly after stimulation. Studies demonstrate that GITRL can neutralise the suppressive effects of CD4+CD25+ regulatory T cells and can also provide a co-stimulatory signal for both naive and primed T cells, suggesting a key role for GITRL in the regulation of T cell-mediated immunity.Synonyms: AITRL, Activation-inducible TNF-related ligand, GITRL, Glucocorticoid-induced TNF-related ligand, TL6, Tumor necrosis factor ligand superfamily member 18, hGITRL

ID gène: 10090

UniProt: Q7TS55