Integrin beta 2 anticorps (PE)

N° du produit ABIN120422

L’anticorps anti-Integrin beta 2 Monoclonal Souris est utilisé pour la détection de Integrin beta 2 dans des échantillons de Rat. Il a été validé pour FACS.

Aperçu rapide pour Integrin beta 2 anticorps (PE) (ABIN120422)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: WT-3

Détail du produit anti-Integrin beta 2 anticorps (PE)

Specificité: This antibody recognises CD18 (LFA-1), a 95-100 kDa cell surface glycoprotein expressed as a heterodimer with CD11a, b or c. Functionally it inhibits homotypic aggregation of PHA blasts. It also blocks binding of rat lymphocytes to purified rat ICAM-1.

Purification: Affinity chromatography on Protein G

Immunogène: FTL-43. Lymph node cells from immunised BALB/c mice were fused with cells from the PAI mouse myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water

Buffer: PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Lyophilized: Store at -20 °C up to 24 months. Reconstituted: Store in aliquots at -20 °C for up to 6 months. Avoid multiple freeze/thaw cycles.

Date de péremption: 6 months

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: CD18 / ITGB2

Sujet: CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7

ID gène: 25021

NCBI Accession: NP_036843

UniProt: Q9JI30

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation