IFNA anticorps

N° du produit ABIN121866

Détail du produit anti-IFNA anticorps

Antigène: IFNA (Interferon alpha (IFNA))

Reactivité: Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNA est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography on protein G

Immunogène: Recombinant chicken Interferon alpha

Information d'application

Indications d'application: ELISA. Western Blot: This antibody cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma, this antibdoy detects a band of approximately 19 kDa. Functional Assays. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur IFNA

Antigène: IFNA (Interferon alpha (IFNA))

Autre désignation: Interferon alpha (IFN Alpha) (IFNA Produits)

Synonymes: anticorps IFN-alphaO, anticorps IFN-ALPHA-1, anticorps IFN1@, anticorps Ifa, anticorps Ifa8, anticorps interferon alpha 16, anticorps interferon, alpha 1, anticorps interferon alpha, anticorps interferon-alpha, anticorps IFNA16, anticorps IFNA1, anticorps Ifna, anticorps IFNA

Sujet: The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon

Pathways: Signalistation JAK/STAT, Signalisation TLR, Hepatitis C, Inflammasome