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MAP2K7 anticorps

L’anticorps Souris Monoclonal anti-MAP2K7 a été validé pour WB, IF, IHC (fro) et EIA. Il convient pour détecter MAP2K7 dans des échantillons de Humain, Souris, Rat et Chien.
N° du produit ABIN126842

Aperçu rapide pour MAP2K7 anticorps (ABIN126842)

Antigène

Voir toutes MAP2K7 Anticorps
MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Reactivité

  • 86
  • 55
  • 52
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Humain, Souris, Rat, Chien

Hôte

  • 99
  • 4
Souris

Clonalité

  • 91
  • 12
Monoclonal

Conjugué

  • 40
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Cet anticorp MAP2K7 est non-conjugé

Application

  • 73
  • 28
  • 26
  • 26
  • 19
  • 17
  • 9
  • 8
  • 8
  • 7
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone

10F7
  • Specificité

    This antibody specifically recognizes the N-terminus of MKK7.

    Attributs du produit

    Synonyms: MAPK/ERK kinase 7, JNK-activating kinase 2, c-Jun N-terminal kinase kinase 2, MAPKK 7,NKK2, MEK7, MKK7, MAP kinase kinase 7, Dual specificity mitogen-activated protein kinasekinase 7

    Purification

    Size exclusion chromatography

    Ingrédients

    incl. positive Control

    Immunogène

    Synthetic peptide conjugated to KLH

    Isotype

    IgG1
  • Indications d'application

    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from untreated SW480 cells. ELISA: 0.1 μg/mL. Immunocytochemistry. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Restore with 1 mL H2O (15 min, RT).

    Buffer

    1 mL2 x PBS containing 0.09 % Sodium Azide, PEG and Sucrose

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C/-80 °C

    Stockage commentaire

    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

    Autre désignation

    MAP2K7

    Sujet

    The stress response of mammalian cells results in activation of kinases of the SAPK1 and SAPK2 families. The SAP kinases are specifically activated by dual phosphorylation of a conserved T-X-Y motif by MAP kinase kinases (MKK). The 3 isoforms of the SAPK1 family (SAPK1α/jnk2, SAPK1β/jnk3, SAPK1γ/jnk1) are synergistically activated by phosphorylation of the threonine residue by MKK7 and the tyrosine residue by MKK4.Synonyms: Dual specificity mitogen-activated protein kinase kinase 7, JNK-activating kinase 2, MAP kinase kinase 7, MAPK/ERK kinase 7, MAPKK 7, MEK7, MKK7, NKK2, c-Jun N-terminal kinase kinase 2

    Poids moléculaire

    45 kDa

    ID gène

    5609

    UniProt

    O14733

    Pathways

    Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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