PTK2B anticorps (pTyr402)

N° du produit ABIN126880

Détail du produit anti-PTK2B anticorps

Antigène: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Épitope: pTyr402

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTK2B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody specifically interacts with activated Pyk2/CAKβ phosphorylated at tyrosine 402. The antibody does not crossreact with the non-phosphorylated form of Pyk2/CAKβ nor with unrelated phosphorylation sites.

Attributs du produit: Synonyms: PYK2, RAFTK, Protein tyrosine kinase 2 beta, Focal adhesion kinase 2, CAK-beta, CADTK,Proline-rich tyrosine kinase 2, Cell adhesion kinase beta, Calcium-dependent tyrosinekinase, Related adhesion focal tyrosine kinase

Purification: Size exclusion chromatography

Immunogène: Synthetic phosphopeptide conjugated to KLH

Clone: 14F6

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.05 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL H2O (15 min, RT).

Buffer: 1 mL2 x PBS / 0.09 % Na-azide / PEG and Sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PTK2B

Antigène: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Autre désignation: FAK2 / PTK2B (PTK2B Produits)

Synonymes: anticorps CADTK, anticorps CAKB, anticorps FADK2, anticorps FAK2, anticorps PKB, anticorps PTK, anticorps PYK2, anticorps RAFTK, anticorps CAKbeta, anticorps E430023O05Rik, anticorps Raftk, anticorps Pyk2, anticorps fak1b, anticorps ptk2.2, anticorps ptk2b, anticorps si:ch1073-355e8.1, anticorps protein tyrosine kinase 2 beta, anticorps PTK2 protein tyrosine kinase 2 beta, anticorps protein tyrosine kinase 2aa, anticorps PTK2B, anticorps Ptk2b, anticorps ptk2aa

Sujet: Proline-rich tyrosine kinase 2 (Pyk2, also known as cellular adhesion kinase β, CAK β) is a 116 kDa cytoplasmic tyrosine kinase. Pyk2 is rapidely phosphorylated on tyrosine residues in response to activation by G-protein-coupled receptors as well as stress signals. Phosphorylation of Pyk2 leads to activation of stress-activated kinase 1 and 2 (SAPK1 and SAPK2).Synonyms: CADTK, CAK-beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, PYK2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, RAFTK, Related adhesion focal tyrosine kinase

ID gène: 2185

UniProt: Q14289

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling