TRAIL anticorps

N° du produit ABIN126992

L’anticorps anti-TRAIL Polyclonal Lapin est utilisé pour la détection de TRAIL dans des échantillons de Humain. Il a été validé pour WB, Func et EIA.

Aperçu rapide pour TRAIL anticorps (ABIN126992)

Antigène: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAIL est non-conjugé

Application: Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)

Détail du produit anti-TRAIL anticorps

Specificité: The antibody detects a 32 kDa protein, corresponding to the apparent molecular weight of TRAIL on SDS-PAGE immunoblots, in human cell lines.

Purification: Affinity purified

Information d'application

Indications d'application: Western Blot: 0.5-1 μg/mL. ELISA: 2-3 μg/mL. Neutralization: 5-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur TRAIL

Antigène: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Autre désignation: CD253 / TRAIL

Sujet: TRAIL (TNF-related apoptosis-inducing ligand), a member of the TNF ligand family, is a type II membrane protein and expressed in a variety of human tissues. Two death domains containing receptors DR4 and DR5 have been identified as the receptors for TRAIL and two decoy receptors designated DcR1 and DcR2 inhibit TRAIL function. The multiple receptors suggest a complex role for regulation of signaling by the cytokine. TRAIL induces apoptosis and NF-kB activation in many tissues and cells.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10

ID gène: 8743

NCBI Accession: NP_003801

UniProt: P50591

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity