IRAK4 anticorps (C-Term)

N° du produit ABIN127206

Cet anticorps anti-IRAK4 Polyclonal Lapin (ABIN127206) détecte spécifiquement IRAK4 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IRAK4 anticorps (C-Term) (ABIN127206)

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRAK4 anticorps

Épitope: C-Term

Specificité: The antibody recognizes 50 kDa IRAK-4.

Purification: Affinity Purified

Immunogène: Synthetic peptide mapping to the C-terminus of human IRAK-4.

Information d'application

Indications d'application: Western Blot: 2-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur IRAK4

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Autre désignation: IRAK4

Sujet: The IRAK family members play an important role in IL-1R/TLR mediated inflammatory responses and in innate immunity. IRAK-4 is a novel member in the IRAK family. Over expression of IRAK-4 activates NFkB and MAPK pathways. Animas and human lacking IRAK-4 are impaired in their responses to viral and bacterial challenges.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64

ID gène: 51135

NCBI Accession: NP_001107654

UniProt: Q9NWZ3

Pathways: Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades