Phospholipase C gamma 2 anticorps (C-Term)

N° du produit ABIN127211

L’anticorps anti-Phospholipase C gamma 2 Polyclonal Lapin est utilisé pour la détection de Phospholipase C gamma 2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC (p) et IP.

Aperçu rapide pour Phospholipase C gamma 2 anticorps (C-Term) (ABIN127211)

Antigène: Phospholipase C gamma 2 (PLCG2)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholipase C gamma 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Détail du produit anti-Phospholipase C gamma 2 anticorps

Épitope: C-Term

Specificité: The antibody recognizes 150 kDa PLCγ2. The antibody does not cross-react with PLCγ1.

Purification: Affinity purified

Immunogène: Synthetic peptide near the C-terminus of human PLCgamma2.

Information d'application

Indications d'application: Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur Phospholipase C gamma 2

Antigène: Phospholipase C gamma 2 (PLCG2)

Autre désignation: PLCG2

Sujet: PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCγ, PLCδ, and PLCε. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCγ2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2

ID gène: 5336

NCBI Accession: NP_002652

UniProt: P16885

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling