PPP1R13L anticorps (Isoform 1)

N° du produit ABIN129682

Détail du produit anti-PPP1R13L anticorps

Antigène: PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Épitope: AA 780-797, Isoform 1

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R13L est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 780-797 of human iASPP protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot.  Specific conditions for reactivity should be optimized by the end user.  Expect bands approximately 100 kDa and 50 kDa in size corresponding to isoforms 1 and 2 respectively of iASPP protein by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-PPP1R13L (ABIN129682)

Liu, Lu, Zhong: "ASPP--Apoptotic specific regulator of p53." dans: Biochimica et biophysica acta, Vol. 1756, Issue 1, pp. 77-80, (2005) (PubMed).

Détails sur PPP1R13L

Antigène: PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Abstract: PPP1R13L Produits

Synonymes: anticorps AV260376, anticorps IASPP, anticorps Nkip1, anticorps wa3, anticorps zgc:113058, anticorps NKIP1, anticorps RAI, anticorps RAI4, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 13 like, anticorps protein phosphatase 1, regulatory subunit 13 like, anticorps protein phosphatase 1 regulatory subunit 13 like, anticorps protein phosphatase 1 regulatory subunit 13 like L homeolog, anticorps Ppp1r13l, anticorps ppp1r13l, anticorps PPP1R13L, anticorps ppp1r13l.L

Sujet: ASPP proteins (ASPP1, ASPP2 and iASPP) represent a new family of p53 binding proteins.  ASPP1 and ASPP2 bind and enhance p53-mediated apoptosis. In contrast, the third member, iASPP, functionally inactivates p53.  iASPP (also called protein phosphatase 1 regulatory (inhibitor) subunit 13 like protein, Inhibitor of ASPP protein, Protein iASPP, PPP1R13B-like protein and NFkB-interacting protein 1) plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. iASPP blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1.
Synonyms: inhibitor of apoptosis stimulating protein of p53 antibody, Inhibitor of ASPP protein antibody, NFkB interacting protein 1 antibody, NKIP1 antibody, PPP1R13B-like protein antibody

ID gène: 10848, 63003907

UniProt: Q8WUF5