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CD28 anticorps

CD28 Reactivité: Souris FACS Hôte: Hamster Monoclonal 37-51 unconjugated
N° du produit ABIN135184
  • Antigène Voir toutes CD28 Anticorps
    CD28
    Reactivité
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    Souris
    Hôte
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    Hamster
    Clonalité
    • 200
    • 74
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    Monoclonal
    Conjugué
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    Cet anticorp CD28 est non-conjugé
    Application
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    Flow Cytometry (FACS)
    Specificité
    Mouse CD28, Mr 40 kDa
    Attributs du produit
    Hamster Anti-Mouse CD28-LE/AF
    niveau d'endotoxine
    Low endotoxin
    Immunogène
    C57BL/6N mouse T cell lymphoma EL-4 cell line
    Clone
    37-51
    Isotype
    IgG
    Top Product
    Discover our top product CD28 Anticorps primaire
  • Indications d'application
    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Activ - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vitro costimulation of T cells and NK cells

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Agent conservateur
    Azide free
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Antigène
    CD28
    Autre désignation
    CD28 (CD28 Produits)
    Synonymes
    anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L
    Sujet
    CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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