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CD28 anticorps

CD28 Reactivité: Souris FACS Hôte: Hamster Monoclonal PV-1 unconjugated
N° du produit ABIN135185
  • Antigène Voir toutes CD28 Anticorps
    CD28
    Reactivité
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    Hôte
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    Hamster
    Clonalité
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    Monoclonal
    Conjugué
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    Cet anticorp CD28 est non-conjugé
    Application
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    Flow Cytometry (FACS)
    Specificité
    Mouse CD28, Mr 40 kDa
    Attributs du produit
    Hamster Anti-Mouse CD28-UNLB
    Purification
    Purified
    Immunogène
    C57BL/6N mouse T cell lymphoma EL4 cell line
    Clone
    PV-1
    Isotype
    IgG
    Top Product
    Discover our top product CD28 Anticorps primaire
  • Indications d'application
    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE, APC, and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vitro costimulation of T cells and NK cells

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CD28
    Autre désignation
    CD28 (CD28 Produits)
    Synonymes
    anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L
    Sujet
    CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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