NADPH Oxidase 4 anticorps (AA 201-300)
Aperçu rapide pour NADPH Oxidase 4 anticorps (AA 201-300) (ABIN1385266)
Antigène
Voir toutes NADPH Oxidase 4 (NOX4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 201-300
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human NOX4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- NADPH Oxidase 4 (NOX4)
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Autre désignation
- NADPH oxidase 4
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Sujet
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Synonyms: Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX 1, KOX, Kox-1, NADPH, NADPH oxidase 4, Nox4, NOX4_HUMAN, Renal NADPH-oxidase, RENOX.
Background: Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
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ID gène
- 50507
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UniProt
- Q9NPH5
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Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
Antigène
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