TAS2R38 anticorps (AA 151-250)

N° du produit ABIN1385568

Détail du produit anti-TAS2R38 anticorps

Antigène: TAS2R38 (Taste Receptor, Type 2, Member 38 (TAS2R38))

Épitope: AA 151-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAS2R38 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain

Homologie: Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human T2R38/TAS2R38

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TAS2R38 (ABIN1385568)

Gaida, Dapunt, Hänsch: "Sensing developing biofilms: the bitter receptor T2R38 on myeloid cells." dans: Pathogens and disease, Vol. 74, Issue 3, (2016) (PubMed).

Maurer, Wabnitz, Kahle, Stegmaier, Prior, Giese, Gaida, Samstag, Hänsch: "Tasting Pseudomonas aeruginosa Biofilms: Human Neutrophils Express the Bitter Receptor T2R38 as Sensor for the Quorum Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone." dans: Frontiers in immunology, Vol. 6, pp. 369, (2015) (PubMed).

Détails sur TAS2R38

Antigène: TAS2R38 (Taste Receptor, Type 2, Member 38 (TAS2R38))

Autre désignation: T2R38 (TAS2R38 Produits)

Synonymes: anticorps PTC, anticorps T2R38, anticorps T2R61, anticorps Tas2r38, anticorps taste 2 receptor member 38, anticorps taste receptor, type 2, member 138, anticorps TAS2R38, anticorps Tas2r138

Sujet:

Synonyms: PTC, PTC bitter taste receptor, T2R38, T2R61, taste receptor, type 2, member 38, T2R38_HUMAN.

Background: The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R38 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Variations in T2R38 are associated with the ability to taste the bitter chemical phenylthiocarbamide (PTC), also called thiourea tasting.

ID gène: 5726