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Adracalin anticorps (AA 51-150)

AAAS Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1385752
  • Antigène Voir toutes Adracalin (AAAS) Anticorps
    Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))
    Épitope
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 30
    • 4
    • 2
    Humain
    Hôte
    • 26
    • 4
    Lapin
    Clonalité
    • 27
    • 3
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Adracalin est non-conjugé
    Application
    • 30
    • 12
    • 12
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Cow
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Adracalin
    Isotype
    IgG
    Top Product
    Discover our top product AAAS Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))
    Autre désignation
    Adracalin (AAAS Produits)
    Synonymes
    anticorps zgc:85873, anticorps aladin, anticorps Aladin, anticorps AAA, anticorps AAASb, anticorps ADRACALA, anticorps ADRACALIN, anticorps ALADIN, anticorps D030041N15Rik, anticorps GL003, anticorps aladin WD repeat nucleoporin, anticorps achalasia, adrenocortical insufficiency, alacrimia, anticorps aladin WD repeat nucleoporin L homeolog, anticorps Aaas, anticorps aaas, anticorps aaas.L, anticorps AAAS
    Sujet

    Synonyms: AAA, AAAS, AAASb, Achalasia adrenocortical insufficiency alacrimia Allgrove triple A, Achalasia adrenocortical insufficiency alacrimia, ADRACALA, Aladin, Allgrove triple A, DKFZp586G1624, GL003, AAAS_HUMAN.

    Background: Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.

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