FZD9 anticorps (AA 185-270)

N° du produit ABIN1386280

Cet anticorps Lapin Polyclonal détecte spécifiquement FZD9 dans WB, ELISA, ICC et IF (cc). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour FZD9 anticorps (AA 185-270) (ABIN1386280)

Antigène: FZD9 (Frizzled Family Receptor 9 (FZD9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-FZD9 anticorps

Épitope: AA 185-270

Specificité: This antibody may have slight cross reactivity with Frizzled 10.

Réactivité croisée: Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Frizzled 9/CD349

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-FZD9 (ABIN1386280)

Vasyliev, Rodnichenko, Gubar, Zlatska, Gordiienko, Novikova, Zubov: "Large-scale expansion and characterization of human adult neural crest-derived multipotent stem cells from hair follicle for regenerative medicine applications." dans: Experimental oncology, Vol. 39, Issue 3, pp. 171-180, (2017) (PubMed).

Détails sur FZD9

Antigène: FZD9 (Frizzled Family Receptor 9 (FZD9))

Autre désignation: Frizzled 9/CD349

Sujet:

Synonyms: FZD3, CD349, Frizzled-9, Fz-9, hFz9, FzE6, FZD9

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

ID gène: 8326

UniProt: O00144

Pathways: Signalisation WNT