MARCH7 anticorps (AA 65-115)

N° du produit ABIN1387036

Détail du produit anti-MARCH7 anticorps

Antigène: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Épitope: AA 65-115

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MARCH7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IP(1-2 μg)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-MARCH7 (ABIN1387036)

Zhang, Wang, Tian, Li: "Expression of USP7 and MARCH7 Is Correlated with Poor Prognosis in Epithelial Ovarian Cancer." dans: The Tohoku journal of experimental medicine, Vol. 239, Issue 3, pp. 165-75, (2016) (PubMed).

Hu, Meng, Yu, Hu, Mao: "Ubiquitin E3 ligase MARCH7 promotes ovarian tumor growth." dans: Oncotarget, Vol. 6, Issue 14, pp. 12174-87, (2015) (PubMed).

Détails sur MARCH7

Antigène: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Autre désignation: MARCH7 (MARCH7 Produits)

Synonymes: anticorps AXO, anticorps AXOT, anticorps MARCH-VII, anticorps RNF177, anticorps Mar-07, anticorps MARCH7, anticorps axot, anticorps axotrophin, anticorps march-vii, anticorps rnf177, anticorps DKFZp468P155, anticorps Axo, anticorps Axot, anticorps Gtrgeo17, anticorps membrane associated ring-CH-type finger 7, anticorps membrane associated ring-CH-type finger 7 S homeolog, anticorps membrane-associated ring finger (C3HC4) 7, anticorps MARCH7, anticorps march7.S, anticorps march7, anticorps March7

Sujet:

Synonyms: AXO, AXOT, Axotrophin, E3 ubiquitin-protein ligase MARCH7, MARCH VII, MARCH-VII, March7, MARH7_HUMAN, Membrane associated RING CH protein VII, Membrane associated ring finger C3HC4 7 E3 ubiquitin protein ligase, membrane associated ring finger C3HC4 7, Membrane associated RING finger protein 7, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, RING finger protein 177, RNF177.

Background: Axotrophin is a stem cell gene that encodes a protein which is involved in T lymphocyte regulation (especially in regulating the proliferation) and leukemia inhibitory factor (LIF) release. LIF is a neuropoietic cytokine that is important for stem cell regulation and thymocyte stimulation. Both Axotrophin and LIF are linked to transplantation intolerance. Axotrophin is also involved in corpus callosum differentiation and may play a role in glial cell line-derived neurotrophic factor (GDNF)-dependent sensory neuron survival in the substantia gelatinosa of the adult spinal cord. Axotrophin is primarily expressed in the hippocampus, cortex, purkinje and granule cells of the cerebellum.

ID gène: 64844

UniProt: Q9H992