PSMB7 anticorps (pSer214)

N° du produit ABIN1387051

Détail du produit anti-PSMB7 anticorps

Antigène: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Épitope: pSer214

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Proteasome 20S beta 7 around the phosphorylation site of Ser214

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PSMB7

Antigène: PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))

Abstract: PSMB7 Produits

Synonymes: anticorps DDBDRAFT_0185624, anticorps DDBDRAFT_0232933, anticorps DDB_0185624, anticorps DDB_0232933, anticorps AU020723, anticorps MC14, anticorps Z, anticorps 20S proteasome subunit beta-7, anticorps proteasome (prosome, macropain) subunit, beta type, 7 S homeolog, anticorps proteasome subunit beta 7, anticorps proteasome (prosome, macropain) subunit, beta type, 7, anticorps proteasome (prosome, macropain) subunit, beta type 7, anticorps psmB7, anticorps psmb7.S, anticorps PSMB7, anticorps Psmb7

Sujet:

Synonyms: Proteasome 20S beta 7 phospho S214, Proteasome 20S beta 7 phospho Ser214, p-Proteasome 20S beta 7 S214, p-Proteasome 20S beta 7 Ser214,20S Proteasome _7, Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome prosome macropain subunit beta type 7, Proteasome beta 7 subunit, Proteasome catalytic subunit 2, Proteasome subunit alpha, Proteasome subunit beta 7, Proteasome subunit beta type-7, Proteasome subunit Z, PSB7_HUMAN, PSMB7, PUP1.

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity.The proteasome represents a large protein complex that exists inside all eukaryotes and archaea, and in some bacteria. The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis. The most common form of the proteasome, known as the 26S Proteasome, contains one 20S Proteasome core particle structure and two 19S regulatory caps. The 20S Proteasome core is hollow and forms an enclosed cavity, where proteins are degraded, as well as openings at the two ends to allow the target protein to enter. The 20S Proteasome core particle contains many subunits, depending on the organism.

ID gène: 5688

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA