GRIK1 anticorps (AA 181-280)

N° du produit ABIN1387480

Détail du produit anti-GRIK1 anticorps

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Épitope: AA 181-280

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GRIK1/GLR5

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur GRIK1

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Autre désignation: GRIK1/GLR5 (GRIK1 Produits)

Synonymes: anticorps GRIK1, anticorps grik1, anticorps fv36b03, anticorps wu:fv36b03, anticorps EAA3, anticorps EEA3, anticorps GLR5, anticorps GLUR5, anticorps GluK1, anticorps A830007B11Rik, anticorps D16Ium24, anticorps D16Ium24e, anticorps GluK5, anticorps Glur-5, anticorps Glur5, anticorps Glurbeta1, anticorps GluR5, anticorps glutamate ionotropic receptor kainate type subunit 1, anticorps glutamate receptor, ionotropic, kainate 1a, anticorps glutamate receptor, ionotropic, kainate 1, anticorps GRIK1, anticorps grik1a, anticorps Grik1

Sujet:

Synonyms: GluR-5/6/7, EAA3, EEA3, Excitatory amino acid receptor 3, GLR5, GluR-5, GluR5, GluR6, GluR7, Glutamate receptor 5, Glutamate receptor, Glutamate receptor ionotropic kainate 1, GRIK1, GRIK1_HUMAN, Human glutamate receptor GLUR5, ionotropic kainate 1, OTTHUMP00000096569.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity