MAPK12 anticorps (pThr183, pTyr185)

N° du produit ABIN1387757

L’anticorps Lapin Polyclonal anti-MAPK12 a été validé pour WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc) et IF (p). Il convient pour détecter MAPK12 dans des échantillons de Humain.

Aperçu rapide pour MAPK12 anticorps (pThr183, pTyr185) (ABIN1387757)

Antigène: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MAPK12 anticorps

Épitope: pThr183, pTyr185

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SAPK3 around the phosphorylation site of Thr183+Tyr185 [EM(p-T)G(p-Y)VV]

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MAPK12

Antigène: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Autre désignation: SAPK3+

Sujet:

Synonyms: p-SAPK3Thr183+Tyr185, MAP kinase 12, MAP kinase p38 gamma, MAPK 12, Mapk12, Mitogen Activated Protein Kinase 12, ERK6, ERK 6, ERK-6, Extracellular signal-regulated kinase 6, Mitogen activated protein kinase 3, Mitogen activated protein kinase p38 gamma, Mitogen-activated protein kinase 12, Mitogen-activated protein kinase p38 gamma, MK12_HUMAN, P38 GAMMA, P38GAMMA, PRKM12, SAPK 3, SAPK3, Stress Activated Protein Kinase 3, Stress-activated protein kinase 3.

Background: MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38 alpha, p38 beta and p38 gamma, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38 alpha, p38 beta and p38 gamma are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins