CACNA1S anticorps (AA 951-1001)

N° du produit ABIN1387901

Détail du produit anti-CACNA1S anticorps

Antigène: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Épitope: AA 951-1001

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1S est non-conjugé

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CACNA1S

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CACNA1S (ABIN1387901)

Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." dans: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

Détails sur CACNA1S

Antigène: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Autre désignation: CACNA1S (CACNA1S Produits)

Synonymes: anticorps CACNA1S, anticorps cav1.1, anticorps ca(v)1.1, anticorps CACNL1A3, anticorps CCHL1A3, anticorps Cav1.1, anticorps HOKPP, anticorps HOKPP1, anticorps MHS5, anticorps TTPP1, anticorps hypoPP, anticorps AW493108, anticorps Cchl1a3, anticorps fmd, anticorps mdg, anticorps sj, anticorps caV1.1, anticorps calcium voltage-gated channel subunit alpha1 S, anticorps calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog, anticorps calcium channel, voltage-dependent, L type, alpha 1S subunit, anticorps CACNA1S, anticorps cacna1s.S, anticorps Cacna1s

Sujet:

Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1, CACNA1S, CACH1, CACN1, CACNL1A3

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

ID gène: 779

UniProt: Q13698

Pathways: Skeletal Muscle Fiber Development