RECQL5 anticorps (AA 1-100) (Alexa Fluor 488)

N° du produit ABIN1390048

Détail du produit anti-RECQL5 anticorps (Alexa Fluor 488)

Antigène: RECQL5 (RecQ Protein-Like 5 (RECQL5))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECQL5 est conjugé à/à la Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RECQL5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RECQL5

Antigène: RECQL5 (RecQ Protein-Like 5 (RECQL5))

Autre désignation: RECQL5 (RECQL5 Produits)

Synonymes: anticorps RecQ5, anticorps DKFZp459N0627, anticorps recq5, anticorps RECQ5, anticorps Recq5b, anticorps Recql5b, anticorps RecQ like helicase 5, anticorps RecQ helicase-like 5, anticorps ATP-dependent DNA helicase Q5, anticorps RecQ protein-like 5, anticorps RECQL5, anticorps recql5, anticorps LOC100544199, anticorps Recql5

Sujet:

Synonyms: ATP-dependent DNA helicase Q5, DNA helicase, RecQ like type 5, DNA helicase, RECQ-like, type 5, RecQ helicase protein-like 5 beta, RecQ protein-like 5, RecQ protein-like 5, isoform CRA_b, RecQ5, Recq5b, Recql5b.

Background: RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higher frequency of SCE. There are three different RecQL5 isoforms - alpha, beta and gamma, produced by alternative splicing.