HSC70 Interacting Protein HIP anticorps (AA 181-280) (Alexa Fluor 350)

N° du produit ABIN1390275

Détail du produit anti-HSC70 Interacting Protein HIP anticorps (Alexa Fluor 350)

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Épitope: AA 181-280

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSC70 Interacting Protein HIP est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSPABP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HSC70 Interacting Protein HIP

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Autre désignation: ST13 (ST13 Produits)

Synonymes: anticorps CG32789, anticorps Dmel\\CG32789, anticorps anon-EST:fe1A9, anticorps 1110007I03Rik, anticorps 3110002K08Rik, anticorps AW555194, anticorps HIP, anticorps HOP, anticorps HSPABP, anticorps HSPABP1, anticorps PRO0786, anticorps SNC6, anticorps p48, anticorps AAG2, anticorps FAM10A1, anticorps FAM10A4, anticorps P48, anticorps Hsc/Hsp70-interacting protein, anticorps suppression of tumorigenicity 13, anticorps ST13, Hsp70 interacting protein, anticorps suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), anticorps HIP, anticorps St13, anticorps ST13

Sujet:

Synonyms: AAG 2, AAG2, Aging associated protein 2, F10A1_HUMAN, FAM10A1, FAM10A4, FLJ27260, Heat shock 70kD protein binding protein, HIP, HOP, Hsc70 interacting protein, Hsc70-interacting protein, Hsp70 interacting protein, HSPABP 1, HSPABP, HSPABP1, MGC129952, OTTHUMP00000028873, P48 antibody PRO0786, Progesterone receptor associated p48 protein, Progesterone receptor-associated p48 protein, Protein FAM10A1, Putative tumor suppressor ST13, Renal carcinoma antigen NY REN 33, Renal carcinoma antigen NY-REN-33, SNC 6, SNC6, ST 13, ST13, Suppression of tumorigenicity 13, Suppression of tumorigenicity 13 colon carcinoma, Suppression of tumorigenicity 13 protein, Suppression of tumorigenicity protein 13.

Background: Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).

ID gène: 6767

UniProt: P50502