PCYT1A anticorps (AA 201-300) (Alexa Fluor 488)

N° du produit ABIN1390486

Détail du produit anti-PCYT1A anticorps (Alexa Fluor 488)

Antigène: PCYT1A (Phosphate Cytidylyltransferase 1, Choline, alpha (PCYT1A))

Épitope: AA 201-300

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCYT1A est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCYT1A

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PCYT1A

Antigène: PCYT1A (Phosphate Cytidylyltransferase 1, Choline, alpha (PCYT1A))

Autre désignation: PCYT1A (PCYT1A Produits)

Synonymes: anticorps CCTA, anticorps CT, anticorps CTA, anticorps CTPCT, anticorps PCYT1, anticorps CCT-alpha, anticorps CTP, anticorps ccta, anticorps cta, anticorps ctpct, anticorps pcyt1, anticorps CTalpha, anticorps Cctalpha, anticorps Ctpct, anticorps Cttalpha, anticorps zgc:110012, anticorps zgc:110237, anticorps phosphate cytidylyltransferase 1, choline, alpha, anticorps phosphate cytidylyltransferase 1, choline, alpha L homeolog, anticorps phosphate cytidylyltransferase 1, choline, alpha isoform, anticorps phosphate cytidylyltransferase 1, choline, alpha b, anticorps phosphate cytidylyltransferase 1, choline, alpha a, anticorps PCYT1A, anticorps Pcyt1a, anticorps pcyt1a.L, anticorps pcyt1a, anticorps pcyt1ab, anticorps pcyt1aa

Sujet:

Synonyms: CCT A, CCT alpha, CCT-alpha, Choline phosphate cytidylyltransferase A, Choline-phosphate cytidylyltransferase A, CT A, CT antibody CTP:phosphocholine cytidylyltransferase A, CTPCT, PCY1A_HUMAN, PCYT1, Pcyt1a, Phosphate cytidylyltransferase 1 choline alpha, Phosphate cytidylyltransferase 1 choline alpha isoform, Phosphorylcholine transferase A.

Background: Increase in fetal surfactant synthesis and lung maturity is caused by the glucocorticoidal induction of enzymes required for phosphatidylcholine synthesis towards the end of gestation (1). The regulation of gestational age-dependent induction of phosphatidylcholine synthesis by glucocorticoids is still unclear (1). The rate-controlling enzyme in the phosphatidylcholine biosynthetic pathway is CTP-phosphocholine cytidylyltransferase A (CCT A) (24). In cultured eukaryotic cells, this enzyme is essential for survival (3). The alpha isoform is located in the nucleus and is regulated by reversible phosphorylation and membrane association (3). There is significant identity between the alpha-helical membrane-binding domains of CCT A and soybean oleosin (2). Expressed CCT A has lipid-dependent cytidylyltransferase activity (5). The gene which encodes CCT A maps to human chromosome 3q (4).