PPP2R5D anticorps (AA 501-602) (Biotin)

N° du produit ABIN1394527

Détail du produit anti-PPP2R5D anticorps (Biotin)

Antigène: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Épitope: AA 501-602

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R5D est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PPP2R5D

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PPP2R5D

Antigène: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Autre désignation: PPP2R5D (PPP2R5D Produits)

Synonymes: anticorps B56D, anticorps B'delta, anticorps TEG-271, anticorps Tex271, anticorps zgc:73160, anticorps zgc:77529, anticorps ppp2r5d, anticorps MDS026, anticorps protein phosphatase 2 regulatory subunit B'delta, anticorps protein phosphatase 2, regulatory subunit B', delta, anticorps serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, anticorps protein phosphatase 2 regulatory subunit Bdelta, anticorps PPP2R5D, anticorps Ppp2r5d, anticorps ppp2r5d, anticorps LOC100176996, anticorps PPP2R2D

Sujet:

Synonyms: B'delta, Delta isoform of regulatory subunit B56, protein phosphatase 2A, MGC2134, MGC8949, OTTHUMP00000039821, PP2A B subunit B' delta isoform, PP2A B subunit B56 delta isoform, PP2A B subunit PR61 delta isoform, PP2A B subunit R5 delta isoform, Protein phosphatase 2 regulatory subunit B B56 delta isoform, Protein phosphatase 2 regulatory subunit B delta isoform, Serine threonine protein phosphatase 2A 56 kDa regulatory subunit delta isoform, TEG-271, Tex271, 2A5D_HUMAN.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A Alpha and PP2A Beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-Alpha and -A-Beta, PP2A-B-Alpha and -B-Beta, PP2A-C-Alpha and -C-Beta, PP2A-B56-Alpha, -B56-Beta, -B56-gamma and -B56-Delta.

Pathways: Signalisation PI3K-Akt, Activation of Innate immune Response, Toll-Like Receptors Cascades