SCN2B anticorps (AA 65-180) (Alexa Fluor 555)

N° du produit ABIN1395287

Détail du produit anti-SCN2B anticorps (Alexa Fluor 555)

Antigène: SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))

Épitope: AA 65-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN2B est conjugé à/à la Alexa Fluor 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SCN2B

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SCN2B

Antigène: SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))

Autre désignation: SCN2B (SCN2B Produits)

Synonymes: anticorps SCNB2, anticorps 2810451E09Rik, anticorps AI840361, anticorps Gm183, anticorps SCN2B, anticorps sodium voltage-gated channel beta subunit 2, anticorps sodium channel, voltage-gated, type II, beta, anticorps sodium voltage-gated channel beta subunit 2 L homeolog, anticorps SCN2B, anticorps Scn2b, anticorps scn2b.L, anticorps scn2b

Sujet:

Synonyms: Neuronal voltage gated sodium channel beta 2 subunit, Scn 2b, Scn2b, SCN2B_HUMAN, Sodium channel beta 2 subunit, Sodium channel subunit beta 2, Sodium channel subunit beta-2, Sodium channel voltage gated type II beta, Sodium channel voltage gated type II beta polypeptide.

Background: Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.