SLC6A7 anticorps (AA 151-260) (Alexa Fluor 647)

N° du produit ABIN1395300

Détail du produit anti-SLC6A7 anticorps (Alexa Fluor 647)

Antigène: SLC6A7 (Solute Carrier Family 6 (Neurotransmitter Transporter, L-Proline), Member 7 (SLC6A7))

Épitope: AA 151-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC6A7 est conjugé à/à la Alexa Fluor 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLC6A7/PROT

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SLC6A7

Antigène: SLC6A7 (Solute Carrier Family 6 (Neurotransmitter Transporter, L-Proline), Member 7 (SLC6A7))

Autre désignation: SLC6A7/PROT (SLC6A7 Produits)

Synonymes: anticorps slc6a7, anticorps AW455934, anticorps PROT, anticorps Prot, anticorps solute carrier family 6 member 7, anticorps zgc:158225, anticorps solute carrier family 6 (neurotransmitter transporter, L-proline), member 7, anticorps SLC6A7, anticorps zgc:158225, anticorps slc6a7, anticorps Slc6a7

Sujet:

Synonyms: SC6A7_HUMAN, Slc6a7, Sodium-dependent proline transporter, Solute carrier family 6 member 7.

Background: The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.