FNDC1 anticorps (AA 21-120) (Biotin)

N° du produit ABIN1399219

Détail du produit anti-FNDC1 anticorps (Biotin)

Antigène: FNDC1 (Fibronectin Type III Domain Containing Protein 1 (FNDC1))

Épitope: AA 21-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNDC1 est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FNDC1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FNDC1

Antigène: FNDC1 (Fibronectin Type III Domain Containing Protein 1 (FNDC1))

Autre désignation: FNDC1 (FNDC1 Produits)

Synonymes: anticorps AGS8, anticorps FNDC2, anticorps MEL4B3, anticorps RP11-243O10.2, anticorps bA243O10.1, anticorps dJ322A24.1, anticorps 1110027O12Rik, anticorps 1110051A18Rik, anticorps mKIAA1866, anticorps fibronectin type III domain containing 1, anticorps FNDC1, anticorps Fndc1

Sujet:

Synonyms: Activation-associated cDNA protein, AGS8, Expressed in synovial lining protein, fibronectin type III domain containing 2, Fibronectin type III domain-containing protein 1, FNDC1, FNDC1_HUMAN, FNDC2, MEL4B3.

Background: FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.

ID gène: 84624