Transportin 1 anticorps (AbBy Fluor® 647)

N° du produit ABIN1400310

Cet anticorps anti-Transportin 1 est un anticorps Lapin Polyclonal détectant Transportin 1 dans WB et IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Transportin 1 anticorps (AbBy Fluor® 647) (ABIN1400310)

Antigène: Transportin 1 (TNPO1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 1 est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Transportin 1 anticorps (AbBy Fluor® 647)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Transportin 1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Transportin 1

Antigène: Transportin 1 (TNPO1)

Autre désignation: Transportin 1

Sujet:

Synonyms: Importin 2, Importin beta 2, IPO 2, IPO2, Karyopherin importin beta 2, Karyopherin beta 2, KPN B2, KPNB 2, KPNB2, M9 interacting protein, M9 region interacting protein, M9 region interaction protein, M9-interacting protein, MIP 1, MIP, MIP1, TNPO 1, TNPO1, Transportin 1, Transportin, Transportin-1, Transportin1, TRN, TNPO1_HUMAN.

Background: Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.

ID gène: 3842

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events