Transportin 1 anticorps (Biotin)

N° du produit ABIN1400311

Cet anticorps Lapin Polyclonal détecte spécifiquement Transportin 1 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Transportin 1 anticorps (Biotin) (ABIN1400311)

Antigène: Transportin 1 (TNPO1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Transportin 1 anticorps (Biotin)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Transportin 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Transportin 1

Antigène: Transportin 1 (TNPO1)

Autre désignation: Transportin 1

Sujet:

Synonyms: Importin 2, Importin beta 2, IPO 2, IPO2, Karyopherin importin beta 2, Karyopherin beta 2, KPN B2, KPNB 2, KPNB2, M9 interacting protein, M9 region interacting protein, M9 region interaction protein, M9-interacting protein, MIP 1, MIP, MIP1, TNPO 1, TNPO1, Transportin 1, Transportin, Transportin-1, Transportin1, TRN, TNPO1_HUMAN.

Background: Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.

ID gène: 3842

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events