CINP anticorps (Alexa Fluor 647)

N° du produit ABIN1400706

Détail du produit anti-CINP anticorps (Alexa Fluor 647)

Antigène: CINP

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CINP est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CINP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CINP

Antigène: CINP

Autre désignation: CINP (CINP Produits)

Synonymes: anticorps 2810452K22RIK, anticorps RGD1563395, anticorps 1810047K05Rik, anticorps 2810452K22Rik, anticorps cyclin dependent kinase 2 interacting protein, anticorps cyclin-dependent kinase 2-interacting protein, anticorps cyclin-dependent kinase 2 interacting protein, anticorps CINP, anticorps Cinp

Sujet:

Synonyms: CINP protein, CDK2-interacting protein, CINP, CINP_HUMAN, Cyclin dependent kinase 2 interacting protein, Cyclin-dependent kinase 2-interacting protein, MGC849.

Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Specifically, Cdk2 interacts with Cyclins A, B1, B3, D, or E to control cell cycle progression. The Cyclin-dependent kinase 2-interacting protein (CINP) interacts with components of the replication complex and Cdk2 and Cdc7, thereby providing a functional and physical link between Cdk2 and Cdc7 during firing of the origins of replication. However, CINP is phopshorylated by Cdc7, but not by Cdk2. CINP also interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress and G2 checkpoint integrity.

ID gène: 51550