AGXT2L2 anticorps (Alexa Fluor 350)

N° du produit ABIN1400805

Détail du produit anti-AGXT2L2 anticorps (Alexa Fluor 350)

Antigène: AGXT2L2 (Alanine-Glyoxylate Aminotransferase 2-Like 2 (AGXT2L2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGXT2L2 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human AGXT2L2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur AGXT2L2

Antigène: AGXT2L2 (Alanine-Glyoxylate Aminotransferase 2-Like 2 (AGXT2L2))

Autre désignation: AGXT2L2 (AGXT2L2 Produits)

Synonymes: anticorps AGXT2L2, anticorps PHLU, anticorps Agxt2l2, anticorps 2900006B13Rik, anticorps 5-phosphohydroxy-L-lysine phospho-lyase, anticorps 5-phosphohydroxy-L-lysine phospholyase, anticorps PHYKPL, anticorps phykpl, anticorps Phykpl

Sujet:

Synonyms: Alanine glyoxylate aminotransferase 2 like 2, MGC117348, AT2L2_HUMAN.

Background: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.