POP1 anticorps (Alexa Fluor 647)

N° du produit ABIN1400880

Détail du produit anti-POP1 anticorps (Alexa Fluor 647)

Antigène: POP1 (Processing of Precursor 1, Ribonuclease P/MRP Subunit (S. Cerevisiae) (POP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POP1 est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ASC2/POP1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur POP1

Antigène: POP1 (Processing of Precursor 1, Ribonuclease P/MRP Subunit (S. Cerevisiae) (POP1))

Autre désignation: POP1 (POP1 Produits)

Synonymes: anticorps 4932434G09Rik, anticorps POP1 homolog, ribonuclease P/MRP subunit, anticorps processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae), anticorps POP1, anticorps Pop1

Sujet:

Synonyms: PAAD domain only protein, POP1, PYDC1, Pyrin domain containing 1, Pyrin only protein 1, PYDC1_HUMAN.

Background: The death domain (DD) superfamily of proteins share one or more of the following domains: the DD, DED (death-effector domain), CARD (caspase-recruitment domain) and PYD (Pyrin domain). Each of these domains is characterized by a canonical death domain fold, which consists of a bundle of five or six antiparallel -helices. As their names suggest, these domains play prominent roles in programmed cell death. ASC2 (apoptosis-associated speck-like protein containing a CARD 2), also known as Pyrin-only protein 1 or PADD-only protein 1, is an 89 amino acid member of the DD superfamily that contains one Pyrin domain. Localized to the cytoplasm, ASC2 interacts with ASC to modulate NF-B and pro-caspase-1 regulation. ASC2 is predominantly expressed in monocytes, macrophages and granulocytes.

ID gène: 10940