PGGT1B anticorps (Alexa Fluor 350)

N° du produit ABIN1403355

Détail du produit anti-PGGT1B anticorps (Alexa Fluor 350)

Antigène: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGGT1B est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PGGT1B/FNTB

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PGGT1B

Antigène: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Autre désignation: PGGT1B (PGGT1B Produits)

Synonymes: anticorps MGC115505, anticorps BGGI, anticorps GGTI, anticorps 2010207C17Rik, anticorps 2610100E13, anticorps AI451237, anticorps AI551093, anticorps BGG1, anticorps GGT1, anticorps protein geranylgeranyltransferase type I subunit beta, anticorps protein geranylgeranyltransferase type I, beta subunit S homeolog, anticorps protein geranylgeranyltransferase type 1 subunit beta, anticorps protein geranylgeranyltransferase type I, beta subunit, anticorps PGGT1B, anticorps pggt1b.S, anticorps Pggt1b

Sujet:

Synonyms: CAAX farnesyltransferase subunit beta, EC 2.5.1.58, EC=2.5.1.58, Farnesyltransferase, farnesyltransferase CAAX box beta1, farnesyltransferase, CAAX box, beta, FNTB, FNTB_HUMAN, FPTB, FTase beta, FTase-beta, Protein farnesyltransferase subunit beta, RAS proteins prenyltransferase beta, Ras proteins prenyltransferase subunit beta.

Background: Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.

ID gène: 2342