PTPLA anticorps (Biotin)

N° du produit ABIN1404499

Détail du produit anti-PTPLA anticorps (Biotin)

Antigène: PTPLA (Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A (PTPLA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPLA est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Brd4/CAP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PTPLA

Antigène: PTPLA (Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A (PTPLA))

Autre désignation: CAP (PTPLA Produits)

Synonymes: anticorps HACD1, anticorps CAP, anticorps hacd1, anticorps ptpla, anticorps 3-hydroxyacyl-CoA dehydratase 1, anticorps 3-hydroxyacyl-CoA dehydratase 1 L homeolog, anticorps Hacd1, anticorps HACD1, anticorps hacd1.L

Sujet:

Synonyms: Brd4, BRD4_HUMAN, bromodomain containing protein 4, Bromodomain-containing protein 4, CAP, chromosome associated protein, HUNK1, Protein HUNK1.

Background: Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.

ID gène: 23476

UniProt: O60885

Pathways: Regulation of long-term Neuronal Synaptic Plasticity