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DERL1 anticorps (AA 111-220) (HRP)

DERL1 Reactivité: Humain ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1408154
  • Antigène Voir toutes DERL1 Anticorps
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    Épitope
    • 14
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-220
    Reactivité
    • 35
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 34
    • 1
    Lapin
    Clonalité
    • 34
    • 1
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DERL1 est conjugé à/à la HRP
    Application
    • 20
    • 14
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DERLIN-1
    Isotype
    IgG
    Top Product
    Discover our top product DERL1 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    Autre désignation
    DERLIN-1 (DERL1 Produits)
    Synonymes
    anticorps CG10908, anticorps Dmel\\CG10908, anticorps DDBDRAFT_0188135, anticorps DDBDRAFT_0266772, anticorps DDB_0188135, anticorps DDB_0266772, anticorps MGC84200, anticorps wu:fb09d07, anticorps wu:fb94d05, anticorps wu:fj92g12, anticorps zgc:55637, anticorps 1110021N07Rik, anticorps AI195141, anticorps AW551338, anticorps Derlin-1, anticorps derlin-1, anticorps DER-1, anticorps DER1, anticorps RGD1311835, anticorps DERLIN-1, anticorps F17A13.150, anticorps F17A13_150, anticorps Derlin-1, anticorps derlin-1, anticorps derlin-1.1, anticorps hypothetical protein, anticorps Der1-like domain family, member 1, anticorps derlin 1, anticorps derlin 1 L homeolog, anticorps DERLIN-1, anticorps Der-1, anticorps EDI_023440, anticorps PTRG_01331, anticorps derl1, anticorps DERL1, anticorps derl1.L, anticorps Derl1, anticorps DER1
    Sujet

    Synonyms: Derlin1, Derlin1, Derlin 1, DER1, DER-1, DER 1, DERL1_HUMAN.

    Background: Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.

    ID gène
    79139
    UniProt
    Q9BUN8
    Pathways
    ER-Nucleus Signaling
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