MYLK3 anticorps (HRP)

N° du produit ABIN1422988

Cet anticorps Lapin Polyclonal détecte spécifiquement MYLK3 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MYLK3 anticorps (HRP) (ABIN1422988)

Antigène: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK3 est conjugé à/à la HRP

Application: Western Blotting (WB)

Détail du produit anti-MYLK3 anticorps (HRP)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MYLK3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MYLK3

Antigène: MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

Autre désignation: MYLK3

Sujet:

Synonyms: caMLCK, Cardiac MyBP C associated Ca/CaM kinase, Cardiac-MyBP-C-associated Ca/CaM kinase, MLC kinase, MLCK, MLCK2, Mylk3, MYLK3_HUMAN, Myosin light chain kinase 3, Putative myosin light chain kinase 3.

Background: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

Pathways: Regulation of Muscle Cell Differentiation