DLK1 anticorps

N° du produit ABIN1449213

Cet anticorps anti-DLK1 est un anticorps Rat Monoclonal détectant DLK1 dans FACS, IHC (p) et IHC (fro). Adapté pour Souris.

Aperçu rapide pour DLK1 anticorps (ABIN1449213)

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp DLK1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 24-11-14

Détail du produit anti-DLK1 anticorps

Specificité: This antibody reacts with Dlk.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Protein G Agarose Chromatography of hybridoma supernatant

Immunogène: Pref-1-Fc protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % Glycerol, pH 7.2, None

Agent conservateur: Azide free

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur DLK1

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Autre désignation: DLK1

Sujet: Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2

ID gène: 13386

NCBI Accession: NP_034182

UniProt: Q09163