DLK1 anticorps (PE)

N° du produit ABIN1449215

L’anticorps Rat Monoclonal anti-DLK1 a été validé pour FACS. Il convient pour détecter DLK1 dans des échantillons de Souris.

Aperçu rapide pour DLK1 anticorps (PE) (ABIN1449215)

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp DLK1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 24-11-14

Détail du produit anti-DLK1 anticorps (PE)

Specificité: This antibody reacts with Dlk.

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Protein G Agarose Chromatography of hybridoma supernatant

Immunogène: Pref-1-Fc protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 1 mLPBS, 0.09 % Sodium Azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8 °C.

Détails sur DLK1

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Autre désignation: DLK1

Sujet: Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2

ID gène: 13386

NCBI Accession: NP_034182

UniProt: Q09163