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MFGE8 anticorps

Cet anticorps Hamster Monoclonal détecte spécifiquement MFGE8 dans WB et IHC (fro). Il présente une réactivité envers Souris.
N° du produit ABIN1449223

Aperçu rapide pour MFGE8 anticorps (ABIN1449223)

Antigène

Voir toutes MFGE8 Anticorps
MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Reactivité

  • 70
  • 9
  • 5
  • 4
Souris

Hôte

  • 52
  • 23
  • 3
  • 1
Hamster

Clonalité

  • 56
  • 23
Monoclonal

Conjugué

  • 49
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MFGE8 est non-conjugé

Application

  • 62
  • 27
  • 23
  • 20
  • 13
  • 13
  • 13
  • 12
  • 12
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

18A2-G10
  • Specificité

    This antibody reacts with MFG-E8 short and long forms.

    Réactivité croisée (Details)

    Species reactivity (tested):Mouse.

    Purification

    Protein A agarose

    Immunogène

    Recombinant mouse MFG-E8

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 50 % Glycerol, pH 7.2, None

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Upon receipt, store (in aliquots) at -20 °C.
  • Antigène

    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

    Autre désignation

    Lactadherin

    Sujet

    Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing avß3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages.Synonyms: Breast epithelial antigen BA46, HMFG, MFGE8, MFGM, Milk fat globule-EGF factor 8

    ID gène

    4240

    NCBI Accession

    NP_001108086

    UniProt

    Q08431

    Pathways

    SARS-CoV-2 Protein Interactome
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