GCLM anticorps (N-Term)

N° du produit ABIN1449395

Détail du produit anti-GCLM anticorps

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Épitope: AA 1-274, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GCLM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human GCLM (1-274aa) purified from E. coli

Clone: AT2D12

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GCLM

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Autre désignation: GCLM / GLCLR (GCLM Produits)

Synonymes: anticorps Glclr, anticorps GLCLR, anticorps id:ibd3182, anticorps wu:fi24c07, anticorps zgc:55903, anticorps AI649393, anticorps Gcmc, anticorps glutamate-cysteine ligase regulatory subunit, anticorps glutamate cysteine ligase, modifier subunit, anticorps glutamate-cysteine ligase modifier subunit, anticorps glutamate-cysteine ligase, modifier subunit, anticorps glutamate-cysteine ligase, modifier subunit L homeolog, anticorps PTRG_09814, anticorps Gclm, anticorps GCLM, anticorps gclm, anticorps gclm.L

Sujet: GCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer.Synonyms: GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate-cysteine ligase modifier subunit, Glutamate-cysteine ligase regulatory subunit

ID gène: 2730

NCBI Accession: NP_002052

UniProt: P48507