SPINK2 anticorps (C-Term)

N° du produit ABIN1450114

Détail du produit anti-SPINK2 anticorps

Antigène: SPINK2 (serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor) (SPINK2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPINK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid synthetic peptide near the carboxy terminus of Human SPINK2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-SPINK2 (ABIN1450114)

Dietz, Maes, Huang, Yandell, Schlamp, Montgomery, Allingham, Hauser, Nickells: "Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage." dans: PLoS ONE, Vol. 9, Issue 4, pp. e93564, (2014) (PubMed).

Détails sur SPINK2

Antigène: SPINK2 (serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor) (SPINK2))

Autre désignation: SPINK2 (SPINK2 Produits)

Synonymes: anticorps 1700007F22Rik, anticorps AV038945, anticorps HUSI-II, anticorps serine peptidase inhibitor, Kazal type 2, anticorps serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor), anticorps Spink2, anticorps SPINK2

Sujet: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.Synonyms: Acrosin-trypsin inhibitor, HUSI-II, Serine protease inhibitor Kazal-type 2

ID gène: 6691

NCBI Accession: NP_065804