FOXRED2 anticorps (N-Term)

N° du produit ABIN1450133

L’anticorps anti-FOXRED2 Polyclonal Lapin est utilisé pour la détection de FOXRED2 dans des échantillons de Humain. Il a été validé pour WB, IF et EIA.

Aperçu rapide pour FOXRED2 anticorps (N-Term) (ABIN1450133)

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXRED2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-FOXRED2 anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the amino terminus of Human FOXRED2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FOXRED2

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Autre désignation: FOXRED2

Sujet: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.Synonyms: FAD-dependent oxidoreductase domain-containing protein 2

ID gène: 80020

Pathways: SARS-CoV-2 Protein Interactome