FOXRED2 anticorps (AA 44-623)

N° du produit ABIN7601747

Cet anticorps anti-FOXRED2 Polyclonal Lapin (ABIN7601747) détecte spécifiquement FOXRED2 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FOXRED2 anticorps (AA 44-623) (ABIN7601747)

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXRED2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-FOXRED2 anticorps

Épitope: AA 44-623

Fonction: Anti-FOXRED2 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-FOXRED2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FOXRED2

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Autre désignation: FOXRED2

Sujet:

Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

Gene Full Name: FAD dependent oxidoreductase domain containing 2

Poids moléculaire: 80 kDa

ID gène: 80020

UniProt: Q8IWF2

Pathways: SARS-CoV-2 Protein Interactome