FOXRED2 anticorps (AA 44-623) (Biotin)

N° du produit ABIN7989530

Cet anticorps anti-FOXRED2 Polyclonal Lapin conjugué à Biotin (ABIN7989530) détecte spécifiquement FOXRED2 dans ELISA, IHC et WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FOXRED2 anticorps (AA 44-623) (Biotin) (ABIN7989530)

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXRED2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-FOXRED2 anticorps (Biotin)

Épitope: AA 44-623

Fonction: Anti-FOXRED2 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FOXRED2

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Autre désignation: FOXRED2

Sujet:

Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

Gene Full Name: FAD dependent oxidoreductase domain containing 2

ID gène: 80020

UniProt: Q8IWF2

Pathways: SARS-CoV-2 Protein Interactome