TLR8 anticorps (N-Term)
Aperçu rapide pour TLR8 anticorps (N-Term) (ABIN1450150)
Antigène
Voir toutes TLR8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 13 amino acid synthetic peptide near the amino terminus of human TLR8
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TLR8 (Toll-Like Receptor 8 (TLR8))
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Autre désignation
- CD288 / TLR8
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Sujet
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.Synonyms: Toll-like receptor 8, UNQ249/PRO286
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ID gène
- 51311
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NCBI Accession
- NP_619542
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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